Human Notch 3 Protein (NOT-HM403)
$283.50 – $945.00
KACTUS Biosystems Human Notch 3 Protein (NOT-HM403) (catalog No. NOT-HM403) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala40-Glu467.
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| Catalog No. | NOT-HM403 |
|---|---|
| Product Name | Human Notch 3 Protein (NOT-HM403) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CADASIL; Notch homolog 3; Notch-3; NOTCH3 |
| Species | Human |
| Source | HEK293 |
| Accession | Q9UM47 |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | Ala40-Glu467 |
| Molecular Weight | The protein has a predicted MW of 47.7 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
NOT-HM403: Human Notch 3 Protein (NOT-HM403)
Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs
Please remember our product information: Human Notch 3 Protein (NOT-HM403) catalog number: NOT-HM403 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |