Human Kremen-1 Protein (KRE-HM201)
$337.50 – $1,125.00
KACTUS Biosystems Human Kremen-1 Protein (KRE-HM201) (catalog No. KRE-HM201) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Arg21-Thr392.
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| Catalog No. | KRE-HM201 |
|---|---|
| Product Name | Human Kremen-1 Protein (KRE-HM201) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Kremen protein 1; KREMEN; KRM1; KREMEN1 |
| Species | Human |
| Source | HEK293 |
| Accession | Q96MU8-1 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Arg21-Thr392 |
| Molecular Weight | The protein has a predicted MW of 67.6 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
KRE-HM201: Human Kremen-1 Protein (KRE-HM201)
KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds to the mature viral particle above the canyon of the viral protein 1 (VP1) subunit and contacts across two adjacent asymmetry units. The key residues for receptor binding are conserved among most KRM1-dependent enteroviruses, suggesting a uniform mechanism for receptor binding.
Please remember our product information: Human Kremen-1 Protein (KRE-HM201) catalog number: KRE-HM201 KACTUS Biosystems
