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Human IL-7R alpha/CD127 Protein (IL7-HM2RA)
$202.50 – $675.00
KACTUS Biosystems Human IL-7R alpha/CD127 Protein (IL7-HM2RA) (catalog No. IL7-HM2RA) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu21-Gly236.
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| Catalog No. | IL7-HM2RA |
|---|---|
| Product Name | Human IL-7R alpha/CD127 Protein (IL7-HM2RA) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | IL-17R alpha; IL7Ra; CD127; CDW127; ILRA |
| Species | Human |
| Source | HEK293 |
| Accession | P16871-1 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Glu21-Gly236 |
| Molecular Weight | The protein has a predicted MW of 51.6 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
IL7-HM2RA: Human IL-7R alpha/CD127 Protein (IL7-HM2RA)
Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.
Please remember our product information: Human IL-7R alpha/CD127 Protein (IL7-HM2RA) catalog number: IL7-HM2RA KACTUS Biosystems
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