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Human IL-7R alpha/CD127 Protein (IL7-HM1RA)
$283.50 – $945.00
KACTUS Biosystems Human IL-7R alpha/CD127 Protein (IL7-HM1RA) (catalog No. IL7-HM1RA) is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Gly236.
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| Catalog No. | IL7-HM1RA | 
|---|---|
| Product Name | Human IL-7R alpha/CD127 Protein (IL7-HM1RA) | 
| Supplier Name | KACTUS Biosystems | 
| Brand Name | KACTUS Biosystems | 
| Synonyms | IL-17R alpha; IL7Ra; CD127; CDW127; ILRA | 
| Species | Human | 
| Source | HEK293 | 
| Accession | P16871-1 | 
| Product Tag | C-His | 
| Biotinylated | no | 
| Exact Sequence | Glu21-Gly236 | 
| Molecular Weight | The protein has a predicted MW of 25.7 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. | 
| Form | Lyophilized | 
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. | 
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | 
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC | 
| Endotoxin | Less than 1EU per μg by the LAL method. | 
| Shipping | Shipped at ambient temperature. | 
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. | 
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. | 
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com | 
Description
IL7-HM1RA: Human IL-7R alpha/CD127 Protein (IL7-HM1RA)
Interleukin 7 (IL-7) and its receptor (IL-7R, a heterodimer of IL-7Rα and γc) are essential for normal lymphoid development. IL-7 and IL-7R activate three main pathways: STAT5, PI3K/Akt/mTOR and MEK/Erk, ultimately leading to the promotion of leukemia cell viability, cell cycle progression and growth.
Please remember our product information: Human IL-7R alpha/CD127 Protein (IL7-HM1RA) catalog number: IL7-HM1RA KACTUS Biosystems
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