Human IL-17C Protein (ILC-HM417)
$283.50 – $945.00
KACTUS Biosystems Human IL-17C Protein (ILC-HM417) (catalog No. ILC-HM417) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His19-Val197.
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| Catalog No. | ILC-HM417 |
|---|---|
| Product Name | Human IL-17C Protein (ILC-HM417) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CX2; Cytokine CX2; IL17C; IL-17C; IL-17CMGC126884 |
| Species | Human |
| Source | HEK293 |
| Accession | Q9P0M4 |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | His19-Val197 |
| Molecular Weight | The protein has a predicted MW of 22.6 kDa. Due to glycosylation, the protein migrates to 25 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in 50mM MES, 150mM NaCl (PH 6.0). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 50mM MES, 150mM NaCl (PH 6.0). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by SEC-HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ILC-HM417: Human IL-17C Protein (ILC-HM417)
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL‑17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G.
Please remember our product information: Human IL-17C Protein (ILC-HM417) catalog number: ILC-HM417 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |
