Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein (MHC-HM439T)
$675.00 – $2,700.00
KACTUS Biosystems Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein (MHC-HM439T) (catalog No. MHC-HM439T) isisassembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGACGVGK peptide.
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| Catalog No. | MHC-HM439T |
|---|---|
| Product Name | Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein (MHC-HM439T) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | AAV53343.1(HLA-A*11:01)&P61769(B2M)&VVVGACGVGK |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and VVVGACGVGK peptide |
| Molecular Weight | The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
MHC-HM439T: Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein (MHC-HM439T)
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Please remember our product information: Human HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein (MHC-HM439T) catalog number: MHC-HM439T KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |