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Human HLA-A*02
Human HLA-A*02
Human HLA-A*02
Human HLA-A*02

Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein (MHC-HM416T)

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Human HLA-A*02

Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein (MHC-HM416T)

$675.00 – $2,700.00

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$675.00 – $2,700.00

KACTUS Biosystems Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein (MHC-HM416T) (catalog No. MHC-HM416T) isisassembled by biotinylated monomer and streptavidin. It contains Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and HMTEVVRRC peptide.

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SKU: MHC-HM416T
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Catalog No. MHC-HM416T
Product NameHuman HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein (MHC-HM416T)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms MHC; HLA-A; P53; TP53; Antigen NY-CO-13; BCC7; FLJ92943; LFS1; TRP53
Species Human
Source HEK293
Accession A0A140T913(HLA-A*02:01)&P61769(B2M)&HMTEVVRRC
Product Tag C-His-Avi
Biotinylated no
Exact Sequence Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)and HMTEVVRRC peptide
Molecular Weight The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

MHC-HM416T: Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein (MHC-HM416T)

p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.

Please remember our product information: Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Tetramer Protein (MHC-HM416T) catalog number: MHC-HM416T KACTUS Biosystems

Additional information

Ship from Country

USA
Size

100 ug, 500 ug
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