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Human GARP&Latent TGF Beta 2 Complex Protein (GAT-HM402)
$405.00 – $1,350.00
KACTUS Biosystems Human GARP&Latent TGF Beta 2 Complex Protein (GAT-HM402) (catalog No. GAT-HM402) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His20-Leu628(GARP)&Leu21-Ser414(Latent TGF Beta 2).
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| Catalog No. | GAT-HM402 |
|---|---|
| Product Name | Human GARP&Latent TGF Beta 2 Complex Protein (GAT-HM402) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | Q14392(GARP)&P61812-1(Latent TGF Beta 2) |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | His20-Leu628(GARP) & Leu21-Ser414(Latent TGF Beta 2) |
| Molecular Weight | The protein has a predicted MW of 70.3 kDa(GARP)&45.53 kDa(Latent TGF Beta 2). Due to enzyme lysis and glycosylation, the protein migrates to 72-77 kDa(GARP)&13 kDa&46-48 kDa(Latent TGF Beta 2) based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
GAT-HM402: Human GARP&Latent TGF Beta 2 Complex Protein (GAT-HM402)
GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex.
Please remember our product information: Human GARP&Latent TGF Beta 2 Complex Protein (GAT-HM402) catalog number: GAT-HM402 KACTUS Biosystems
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