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Human Factor H/CFH Protein (CFH-HM101)

Human Factor H/CFH Protein (CFH-HM101)

Human Factor H/CFH Protein (CFH-HM101)

$243.00$810.00

In stock

$243.00$810.00

KACTUS Biosystems Human Factor H/CFH Protein (CFH-HM101) (catalog No. CFH-HM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser860-Arg1231.

SKU: CFH-HM101
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Catalog No. CFH-HM101
Product NameHuman Factor H/CFH Protein (CFH-HM101)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms Complement factor H; H factor 1; CFH; HF; HF1; HF2; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; FH; FHL1; HUS
Species Human
Source HEK293
Accession P08603-1
Product Tag C-His
Biotinylated no
Exact Sequence Ser860-Arg1231
Molecular Weight The protein has a predicted MW of 42.8 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

CFH-HM101: Human Factor H/CFH Protein (CFH-HM101)

Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self) can hijack factor H to evade the immune response.

Please remember our product information: Human Factor H/CFH Protein (CFH-HM101) catalog number: CFH-HM101 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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