Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM3D2)
$351.00 – $1,170.00
KACTUS Biosystems Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM3D2) (catalog No. CDH-HM3D2) is expressed from HEK293 with mFc tag at the C-Terminus.It contains Ser567-Gly777.
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| Catalog No. | CDH-HM3D2 |
|---|---|
| Product Name | Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM3D2) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | Q12864 |
| Product Tag | C-mFc |
| Biotinylated | no |
| Exact Sequence | Ser567-Gly777 |
| Molecular Weight | The protein has a predicted MW of 50.18 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
CDH-HM3D2: Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM3D2)
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Please remember our product information: Human CDH17/Cadherin 17 Domain 6-7 Protein (CDH-HM3D2) catalog number: CDH-HM3D2 KACTUS Biosystems