ErbB4/HER4 Rabbit mAb
$148.00 – $548.00
HER4; ALS19; p180erbB4
- Details & Specifications
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| Catalog No. | A19047 |
|---|---|
| Product Name | ErbB4/HER4 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | HER4; ALS19; p180erbB4 |
| Gene Name | ERBB4 |
| Protein Name | ERBB4 |
| Uniprot/Swissprot ID | Q15303 |
| Gene ID | 2066 |
| Clone | ARC2639 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
