DROSHA Rabbit mAb
$148.00 – $548.00
RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976
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| Catalog No. | A19598 |
|---|---|
| Product Name | DROSHA Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976 |
| Gene Name | DROSHA |
| Protein Name | DROSHA |
| Uniprot/Swissprot ID | Q9NRR4 |
| Entrez GeneID | 29102 |
| Clone | ARC0077 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | WB, IF/ICC |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
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