DMAP1 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

DMAP1 Rabbit mAb

$148.00$548.00

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$148.00$548.00

EAF2; SWC4; MEAF2; DNMAP1; DNMTAP1

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SKU: A19281 Categories: ,
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Catalog No. A19281
Product NameDMAP1 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms EAF2; SWC4; MEAF2; DNMAP1; DNMTAP1
Gene Name DMAP1
Protein Name DMAP1
Uniprot/Swissprot ID Q9NPF5
Entrez GeneID 55929
Clone ARC2462
Clonality Monoclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.

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