Cynomolgus IL-31 Protein (IL3-CM131)
$310.50 – $1,035.00
KACTUS Biosystems Cynomolgus IL-31 Protein (IL3-CM131) (catalog No. IL3-CM131) is expressed from HEK293 with His tag at the N-Terminus.It contains Leu27-Thr163.
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| Catalog No. | IL3-CM131 |
|---|---|
| Product Name | Cynomolgus IL-31 Protein (IL3-CM131) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Interleukin-31； IL-31；IL31 |
| Species | Cynomolgus |
| Source | HEK293 |
| Accession | G7PJ78-1 |
| Product Tag | N-His |
| Biotinylated | no |
| Exact Sequence | Leu27-Thr163 |
| Molecular Weight | The protein has a predicted MW of 16.5 kDa. Due to glycosylation, the protein migrates to 23-30 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
IL3-CM131: Cynomolgus IL-31 Protein (IL3-CM131)
Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus. While histamine and neuropeptides have previously been ascribed to play a role in itch that accompanies these diseases, recent evidence suggests that the pruritogenic cytokine interleukin (IL)-31 is a major driver of pruritic responses. IL-31 was originally shown to be produced by activated helper T cells, particularly Th2 cells, mast cells, macrophages and dendritic cells.
Please remember our product information: Cynomolgus IL-31 Protein (IL3-CM131) catalog number: IL3-CM131 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |