Cynomolgus IL-21R Protein (ILR-CM121)
$283.50 – $945.00
KACTUS Biosystems Cynomolgus IL-21R Protein (ILR-CM121) (catalog No. ILR-CM121) is expressed from HEK293 with His tag at the C-Terminus.It contains Cys41-Gly254.
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| Catalog No. | ILR-CM121 |
|---|---|
| Product Name | Cynomolgus IL-21R Protein (ILR-CM121) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Cynomolgus |
| Source | HEK293 |
| Accession | G7Q0S8 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Cys41-Gly254 |
| Molecular Weight | The protein has a predicted MW of 25.70 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
ILR-CM121: Cynomolgus IL-21R Protein (ILR-CM121)
IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORγt expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker in RM B cells, a feature associated with increased apoptosis and a reduced number of these cells in the circulation.
Please remember our product information: Cynomolgus IL-21R Protein (ILR-CM121) catalog number: ILR-CM121 KACTUS Biosystems