Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)
$101.70 – $337.50
KACTUS Biosystems Cynomolgus CTLA-4/CD152 Protein (CTL-CM141) (catalog No. CTL-CM141) is expressed from HEK293 with His tag at the C-Terminus.It contains Ala37-Ser160.
- Details & Specifications
- References
| Catalog No. | CTL-CM141 |
|---|---|
| Product Name | Cynomolgus CTLA-4/CD152 Protein (CTL-CM141) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CTLA4; CD152; ICOS; CELIAC3; GRD4; GSE; ALPS5; IDDM12 |
| Species | Cynomolgus |
| Source | HEK293 |
| Accession | G7PL88-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Ala37-Ser160 |
| Molecular Weight | The protein has a predicted MW of 14.4 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
CTL-CM141: Cynomolgus CTLA-4/CD152 Protein (CTL-CM141)
CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an “off” switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.
Please remember our product information: Cynomolgus CTLA-4/CD152 Protein (CTL-CM141) catalog number: CTL-CM141 KACTUS Biosystems