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Cynomolgus CRTAM Protein (CRM-CM201)

Cynomolgus CRTAM Protein (CRM-CM201)

Cynomolgus CRTAM Protein (CRM-CM201)

$216.00$720.00

In stock

$216.00$720.00

KACTUS Biosystems Cynomolgus CRTAM Protein (CRM-CM201) (catalog No. CRM-CM201) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser18-Gly287.

SKU: CRM-CM201
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Catalog No. CRM-CM201
Product NameCynomolgus CRTAM Protein (CRM-CM201)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms CD355 antigen; CD355; CRTAM
Species Cynomolgus
Source HEK293
Accession XP_005580021.1
Product Tag C-hFc
Biotinylated no
Exact Sequence Ser18-Gly287
Molecular Weight The protein has a predicted MW of 56.6 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

CRM-CM201: Cynomolgus CRTAM Protein (CRM-CM201)

Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

Please remember our product information: Cynomolgus CRTAM Protein (CRM-CM201) catalog number: CRM-CM201 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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