Cynomolgus CDH17/Cadherin 17 Protein (CDH-CM117)
$310.50 – $1,035.00
KACTUS Biosystems Cynomolgus CDH17/Cadherin 17 Protein (CDH-CM117) (catalog No. CDH-CM117) is expressed from HEK293 with His tag at the C-Terminus.It contains Met1-Met795.
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| Catalog No. | CDH-CM117 |
|---|---|
| Product Name | Cynomolgus CDH17/Cadherin 17 Protein (CDH-CM117) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Cadherin-17; BILL-cadherin; LI-cadherin; P130; Cdh17; CDH16; HPT-1; cadherin-16; FLJ26931; MGC138218; MGC142024 |
| Species | Cynomolgus |
| Source | HEK293 |
| Accession | A0A2K5X8I8 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Met1-Met795 |
| Molecular Weight | The protein has a predicted MW of 89.2 kDa. Due to glycosylation, the protein migrates to 105-115 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (PH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 90% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
CDH-CM117: Cynomolgus CDH17/Cadherin 17 Protein (CDH-CM117)
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Please remember our product information: Cynomolgus CDH17/Cadherin 17 Protein (CDH-CM117) catalog number: CDH-CM117 KACTUS Biosystems