CD4 mFluor450(1120144)

CD4 mFluor450(1120144) catalog number: 1120144 Caprico Biotechnologies

CD4 mFluor450(1120144)

$110.00$405.00

In stock

$110.00$405.00

Caprico Biotechnologies CD4 mFluor450 catalog number: 1120144,The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily.

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Catalog No. 1120144
Product NameCD4 mFluor450(1120144)
Supplier Name Caprico Biotechnologies, Inc.
Brand Name Caprico
Accession No. NM_000616.4
Protein Name CD4
Uniprot/Swissprot ID P01730
Gene ID 920
Primary/Secondary Primary
Clone SK3
Clonality Monoclonal
Source/Host Mouse
Reactivity Human
Immunogen Human peripheral blood T cells
Form Of Antibody PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide
Conjugate mFluor™ 450
Purity >95%
Stability & Storage 2-8oC
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Description

1120144:CD4 mFluor450(1120144)

The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).
Please remember our product information: CD4 mFluor450(1120144) catalog number: 1120144 Caprico Biotechnologies

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