CD4 Biotin(112050)
$95.00 – $170.00
Caprico Biotechnologies CD4 Biotin catalog number: 112050，The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily.
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| Catalog No. | 112050 |
|---|---|
| Product Name | CD4 Biotin(112050) |
| Supplier Name | Caprico Biotechnologies, Inc. |
| Brand Name | Caprico |
| Accession No. | NM_000616.4 |
| Protein Name | CD4 |
| Uniprot/Swissprot ID | P01730 |
| Gene ID | 920 |
| Primary/Secondary | Primary |
| Clone | SK3 |
| Clonality | Monoclonal |
| Source/Host | Mouse |
| Reactivity | Cynomolgus monkey, Human, Rhesus |
| Immunogen | Human peripheral blood T cells |
| Form Of Antibody | PBS pH 7.2, 0.09% sodium azide |
| Conjugate | Biotin |
| Purity | >95% |
| Stability & Storage | 2-8oC |
| Note | Products will be shipped from the warehouse in Georgia. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5521 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card. |
Description
112050：CD4 Biotin(112050)
The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).
Please remember our product information: CD4 Biotin(112050) catalog number: 112050 Caprico Biotechnologies