Canine PDGF R beta/CD140b Protein (PGF-DM1RB)
$283.50 – $945.00
KACTUS Biosystems Canine PDGF R beta/CD140b Protein (PGF-DM1RB) (catalog No. PGF-DM1RB) is expressed from HEK293 with His tag at the C-Terminus.It contains Gly32-Val532.
- Details & Specifications
- References
- More Offers
| Catalog No. | PGF-DM1RB |
|---|---|
| Product Name | Canine PDGF R beta/CD140b Protein (PGF-DM1RB) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Canine |
| Source | HEK293 |
| Accession | Q6QNF3 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Gly32-Val532 |
| Molecular Weight | The protein has a predicted MW of 57.25 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PGF-DM1RB: Canine PDGF R beta/CD140b Protein (PGF-DM1RB)
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
Please remember our product information: Canine PDGF R beta/CD140b Protein (PGF-DM1RB) catalog number: PGF-DM1RB KACTUS Biosystems
