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Canine CRTAM Protein (CRM-DM101)

Canine CRTAM Protein (CRM-DM101)

Canine CRTAM Protein (CRM-DM101)

$283.50$945.00

In stock

$283.50$945.00

KACTUS Biosystems Canine CRTAM Protein (CRM-DM101) (catalog No. CRM-DM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Phe18-Gly287.

SKU: CRM-DM101
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Catalog No. CRM-DM101
Product NameCanine CRTAM Protein (CRM-DM101)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Species Canine
Source HEK293
Accession E2QWY2
Product Tag C-His
Biotinylated no
Exact Sequence Phe18-Gly287
Molecular Weight The protein has a predicted MW of 31.19 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

CRM-DM101: Canine CRTAM Protein (CRM-DM101)

Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

Please remember our product information: Canine CRTAM Protein (CRM-DM101) catalog number: CRM-DM101 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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