Biotinylated Human IGF1R/CD221 Protein (IGF-HM41RB)
$472.50 – $1,575.00
KACTUS Biosystems Biotinylated Human IGF1R/CD221 Protein (IGF-HM41RB) (catalog No. IGF-HM41RB) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu31-Asn932.
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Catalog No. | IGF-HM41RB |
---|---|
Product Name | Biotinylated Human IGF1R/CD221 Protein (IGF-HM41RB) |
Supplier Name | KACTUS Biosystems |
Brand Name | KACTUS Biosystems |
Synonyms | CD221; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216 |
Species | Human |
Source | HEK293 |
Accession | P08069 |
Product Tag | C-His-Avi |
Biotinylated | yes |
Exact Sequence | Glu31-Asn932 |
Molecular Weight | The protein has a predicted MW of 105.8 kDa (alpha subunit) and 23 kDa (beta subunit). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result. |
Form | Lyophilized |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per μg by the LAL method. |
Shipping | Shipped at ambient temperature. |
Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
IGF-HM41RB: Biotinylated Human IGF1R/CD221 Protein (IGF-HM41RB)
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target.
Please remember our product information: Biotinylated Human IGF1R/CD221 Protein (IGF-HM41RB) catalog number: IGF-HM41RB KACTUS Biosystems