Anti-p53 WT Unconjugated(102201)
$205.00 – $395.00
Caprico Biotechnologies Anti-p53 WT Unconjugated catalog number:102201，p53 acts as a tumor suppressor in many tumor types; it induces growth arrest or apoptosis depending on the physiological circumstances and cell type.
- Details & Specifications
- References
| Catalog No. | 102201 |
|---|---|
| Product Name | Anti-p53 WT Unconjugated(102201) |
| Supplier Name | Caprico Biotechnologies, Inc. |
| Brand Name | Caprico |
| Accession No. | NM_000546.5 |
| Protein Name | p53 |
| Uniprot/Swissprot ID | P04637 |
| Gene ID | 7157 |
| Primary/Secondary | Primary |
| Clone | PAB1620 |
| Clonality | Monoclonal |
| Source/Host | Mouse |
| Reactivity | Human |
| Immunogen | Mouse VLM tumor cells |
| Form Of Antibody | PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide |
| Conjugate | Unconjugated |
| Purity | >95% |
| Stability & Storage | 2-8oC |
| Note | Products will be shipped from the warehouse in Georgia. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5070 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card. |
Description
102201：Anti-p53 WT Unconjugated(102201)
p53 acts as a tumor suppressor in many tumor types; it induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator, p53 acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
Please remember our product information: Anti-p53 WT Unconjugated(102201) catalog number: 102201 Caprico Biotechnologies