BLU-9931
BLU-9931 (CAS No.: 1538604-68-0), a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU-9931 has significant antitumor activity. >98%...
Nazartinib (EGF-816)
Nazartinib (EGF-816) (CAS No.: 1508250-71-2), a covalent mutant-selective EGFR inhibitor, with Ki and Kinact of 31 nM and 0.222 min-1 on EGFR(L858R/790M) mutant, respectively. >98% Purity. Synonyms: EGF-816, EGF816, EGFR inhibitor, epidermal growth factor receptor inhibitor For...
Bevacizumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
The bevacizumab biosimilar, L234A L235A P329G (LALAPG) Fc silent mutant, can be used for ELISA, neutralization, in vitro and in vivo functional assays such as bioanalytical PK and ADA assays, and those assays for studying...
Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
Pertuzumab biosimilar with the L234A L235A P329G (LALAPG) Fc silent mutation (anti-human HER2 monoclonal antibody, mAb) for in vitro and in vivo assays to study human HER2 biological pathways. The pertuzumab biosimilar with the wild...
Trastuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
Trastuzumab biosimilar with the L234A L235A P329G (LALAPG) Fc silent mutation (anti-human HER2 monoclonal antibody, mAb, clone 4D5-8) for in vitro and in vivo assays to study human HER2 biological pathways. The trastuzumab biosimilar with...