Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
$375.00
Pertuzumab biosimilar with the L234A L235A P329G (LALAPG) Fc silent mutation (anti-human HER2 monoclonal antibody, mAb) for in vitro and in vivo assays to study human HER2 biological pathways. The pertuzumab biosimilar with the wild type Fc, the corresponding human IgG1 isotype controls and mutants, and the antibody dilution buffer are also available.
Synonyms: Receptor tyrosine-protein kinase erbB-2, CD340, cluster of differentiation 340, proto-oncogene Neu, Erbb2 (rodent), ERBB2 (human), erythroblastic oncogene B 2, human epidermal growth factor receptor 2.
- Product Details
- Description
- Additional information
- More Offers
| Catalog No. | C006P-AAG |
|---|---|
| Product Name | Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Source/Host | The anti-HER2 monoclonal antibody pertuzumab biosimilar L234A L235A P329G (LALAPG) Fc silent mutant was produced in mammalian cells. |
| Specificity/Sensitivity | The in vivo grade pertuzumab biosimilar L234A L235A P329G (LALAPG) Fc silent mutant specifically binds to the human HER2/ErbB-2/c-neu. |
| Applications | ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab. |
| Form Of Antibody | 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives. |
| Endotoxin | < 0.1 EU per 1 ug of the protein by the LAL method. |
| Purity | >95% by SDS-PAGE under reducing conditions and HPLC. |
| Shipping | The recombinant monoclonal antibody pertuzumab biosimilar L234A L235A P329G (LALAPG) Fc silent mutant is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied. |
| Note | Pertuzumab biosimilar CHO stable cell line is available for licensing to manufacture the pertuzumab biosimilar protein. The research grade pertuzumab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com Or leave a message with a formal purchase order (PO) Or credit card. |
Description
C006P-AAG: Pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
Recombinant humanized IgG1 Monoclonal Antibody.
Background
Pertuzumab, a humanized monoclonal antibody, inhibits HER dimerization and is used for the treatment of HER2-positive metastatic breast cancer, in combination with trastuzumab and docetaxel. By binding to HER2, Pertuzumab inhibits the dimerization of HER2 with other HER receptors, resulting in slowed tumor growth.
Syd Labs also provides the following anti-ErbB/HER antibody biosimilar proteins:
Cetuximab biosimilar, research grade, anti-human EGFR monoclonal antibody
Cetuximab biosimilar, L234A L235A P329G (LALAPG) Fc silent mutant
Panitumumab biosimilar, research grade, anti-human EGFR monoclonal antibody
Panitumumab biosimilar, L234A L235A P329G (LALAPG) Fc silent mutant
Trastuzumab Biosimilar, research grade, anti-human Her2 monoclonal antibody
Trastuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc silent mutant
Syd Labs provides a number of research grade antibody biosimilar proteins with competitive prices starting from $3/mg. Syd Labs also introduces mutations to the antibody biosimilars including engineering or switching the isotypes or Fc engineering, such as Fc silent.
Research grade pertuzumab biosimilar, anti-human HER2 monoclonal antibody
Syd Labs also produces the in vivo grade isotype control antibodies. Some customers purchase them for in vitro assays such as flow cytometry or immunohistochemistry (IHC) because the prices are too good if compared to those research reagents of antibody isotype controls. Syd Labs provides the following in vivo grade recombinant human IgG1 kappa isotype control antibody proteins and mutants:
In vivo grade recombinant human IgG1 isotype control antibody
In vivo grade recombinant human IgG1 Fc protein
In vivo grade recombinant human IgG1-L234A L235A P329G (LALAPG) isotype control antibody
Frequent questions related to “pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc silent mutant”:
Does pertuzumab bind mouse HER2?
Is pertuzumab humanized?
What is the mechanism of action for pertuzumab?
Popular searches related to “pertuzumab Biosimilar, L234A L235A P329G (LALAPG) Fc silent mutant”:
pertuzumab monoclonal antibody
pertuzumab purchase
pertuzumab mechanism of action
pertuzumab price
HER2 mouse cell line
Cetuximab Biosimilar research grade
HER1
ErbB-1
EGFR
Panitumumab Biosimilar research grade
Trastuzumab Biosimilar research grade
HER2
ErbB-2
c-neu
Additional information
| Ship from Country | USA |
|---|---|
| Size | 0.5 mg |