IL21R Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

IL21R Rabbit pAb

$108.00$488.00

In stock

$108.00$488.00

NILR; CD360; IMD56

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SKU: A7468
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Catalog No. A7468
Product NameIL21R Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms NILR; CD360; IMD56
Gene Name IL21R
Protein Name IL21R
Uniprot/Swissprot ID Q9HBE5
Entrez GeneID 50615
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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