BEST1 Rabbit pAb
$108.00 – $488.00
ARB; BMD; BEST; RP50; VMD2; TU15B; Best1V1Delta2
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| Catalog No. | A14070 |
|---|---|
| Product Name | BEST1 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | ARB; BMD; BEST; RP50; VMD2; TU15B; Best1V1Delta2 |
| Summary | Rabbit IgG polyclonal antibody for RUNDC1 detection. Tested with WB, FCM, Direct ELISA in Human;Monkey. |
| Gene Name | BEST1 |
| Gene Full Name | RUN domain containing 1 |
| Protein Name | BEST1 |
| Uniprot/Swissprot ID | O76090 |
| Uniprot ID | Q96C34 |
| Entrez GeneID | 7439 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB |
| Application Details | Western blot|0.25-0.5 μg/ml|Human, Monkey| Flow Cytometry|1-3 μg/1x10^6 cells|Human| Direct ELISA|0.1-0.5 μg/ml|Human| |
| Reactivity | Human, Mouse |
| Immunogen | E.coli-derived human RUNDC1 recombinant protein (Position: E125-K607). |
| Purification | Immunogen affinity purified. |
| Form Of Antibody | Lyophilized |
| Reconstitution | Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
| Contents | E.coli-derived human RUNDC1 recombinant protein (Position: E125-K607). |
| Conjugate | Unconjugated |
| Stability & Storage | At -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freezing and thawing. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |