DAB2 Rabbit pAb
$278.00 – $488.00
DAB2 Rabbit pAb
SKU: A3822
- Product Details
- Description
- Additional information
- More Offers
| Catalog No. | A3822 |
|---|---|
| Product Name | DAB2 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | DOC2; DOC-2 |
| Gene Name | DAB2 |
| Protein Name | DAB2 |
| Uniprot ID | P98082 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB, FC |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 μL, 200 μL |
No more offers for this product!