TPMT Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

TPMT Rabbit pAb

$108.00$488.00

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$108.00$488.00

TPMTD

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SKU: A1017
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Catalog No. A1017
Product NameTPMT Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms TPMTD
Gene Name TPMT
Protein Name TPMT
Uniprot/Swissprot ID P51580
Entrez GeneID 7172
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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