SPHK1 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

SPHK1 Rabbit pAb

$108.00$488.00

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$108.00$488.00

SPHK

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SKU: A0660
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Catalog No. A0660
Product NameSPHK1 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms SPHK
Gene Name SPHK1
Protein Name SPHK1
Uniprot/Swissprot ID Q9NYA1
Entrez GeneID 8877
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Phosphorylation of this protein alters its catalytic activity and promotes its translocation to the plasma membrane. Alternative splicing results in multiple transcript variants encoding different isoforms.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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