SLC12A3 Rabbit pAb
$108.00 – $488.00
NCC; TSC; NCCT
SKU: A18382
- Product Details
- Description
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| Catalog No. | A18382 |
|---|---|
| Product Name | SLC12A3 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | NCC; TSC; NCCT |
| Gene Name | SLC12A3 |
| Protein Name | SLC12A3 |
| Uniprot/Swissprot ID | P55017 |
| Entrez GeneID | 6559 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB |
| Reactivity | Human, Mouse, Monkey |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter’s syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |
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