Phospho-BCAR1-Y165 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-BCAR1-Y165 Rabbit pAb

$128.00$548.00

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$128.00$548.00

CAS; CAS1; CASS1; CRKAS; P130Cas

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SKU: AP0813
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Catalog No. AP0813
Product NamePhospho-BCAR1-Y165 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms CAS; CAS1; CASS1; CRKAS; P130Cas
Gene Name BCAR1
Protein Name BCAR1
Uniprot/Swissprot ID P56945
Entrez GeneID 9564
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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