NEDD4L Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

NEDD4L Rabbit pAb

$108.00$488.00

In stock

$108.00$488.00

RSP5; PVNH7; NEDD4-2; NEDD4.2; hNEDD4-2

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SKU: A8085
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Catalog No. A8085
Product NameNEDD4L Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms RSP5; PVNH7; NEDD4-2; NEDD4.2; hNEDD4-2
Gene Name NEDD4L
Protein Name NEDD4L
Uniprot/Swissprot ID Q96PU5
Entrez GeneID 23327
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IHC-P, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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