MAP3K5 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

MAP3K5 Rabbit pAb

$108.00$488.00

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$108.00$488.00

ASK1; MEKK5; MAPKKK5

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SKU: A0283
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Catalog No. A0283
Product NameMAP3K5 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms ASK1; MEKK5; MAPKKK5
Gene Name MAP3K5
Protein Name MAP3K5
Uniprot/Swissprot ID Q99683
Entrez GeneID 4217
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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