EDN3 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

EDN3 Rabbit pAb

$108.00$488.00

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$108.00$488.00

ET3; ET-3; WS4B; HSCR4; PPET3

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SKU: A1045
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Catalog No. A1045
Product NameEDN3 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms ET3; ET-3; WS4B; HSCR4; PPET3
Gene Name EDN3
Protein Name EDN3
Uniprot/Swissprot ID P14138
Entrez GeneID 1908
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Additional information

Ship from Country

USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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