CDKN1B/p27KIP1 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

CDKN1B/p27KIP1 Rabbit pAb

$108.00$488.00

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$108.00$488.00

KIP1; MEN4; CDKN4; MEN1B; P27KIP1

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SKU: A0290
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Catalog No. A0290
Product NameCDKN1B/p27KIP1 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms KIP1; MEN4; CDKN4; MEN1B; P27KIP1
Gene Name CDKN1B
Protein Name CDKN1B
Uniprot/Swissprot ID P46527
Entrez GeneID 1027
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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