ASPH Rabbit pAb

Catalog No.	A13153
Product Name	ASPH Rabbit pAb
Supplier Name	ABclonal, Inc.
Brand Name	Abclonal
Synonyms	AAH; BAH; HAAH; JCTN; FDLAB; junctin; CASQ2BP1
Gene Name	ASPH
Protein Name	ASPH
Uniprot/Swissprot ID	Q12797
Entrez GeneID	444
Clonality	Polyclonal
Source/Host	Rabbit
Applications	WB
Reactivity	Human
Conjugate	Unconjugated
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis.

Additional information

Ship from Country	USA
Size	20 ul, 100 ul, 200 ul, 50 ul

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