ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb (A22592)
$218.00 – $568.00
Abclonal ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb (Catalog Number: A22592) Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.
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| Catalog No. | A22592 |
|---|---|
| Product Name | ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb (A22592) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1 |
| Gene Name | F11R |
| Protein Name | F11R |
| Uniprot/Swissprot ID | Q9Y624 |
| Entrez GeneID | 50848 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | FC |
| Reactivity | Human |
| Conjugate | ABflo® 488. Ex:491nm. Em:516nm. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A22592: ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5′ alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Immunogen Information about ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb (A22592)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 28-242 of human JAM-A/CD321/F11R (NP_058642.1).
Sequence：SVTVHSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEGGNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVERNVGVIVAA
Gene ID：50848
Swiss prot：Q9Y624
Synonyms：JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1
Calculated MW：27kDa/32kDa
Observed MW：
Images of ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb (A22592)
Flow cytometry:1X10^6 U-2 OS cells (negative control, Left) and HT-29 cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb(A22592, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry:1X10^6 HT-29 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb(A22592, 5 μl/Test, right).
Please remember our product information: ABflo® 488 Rabbit anti-Human JAM-A/CD321/F11R mAb (Catalog Number: A22592) Abclonal
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 μg, 25 μg, 50 μg |