XIAP Polyclonal Antibody
$350.00
Conditions of optimal XIAP polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA003721-PA1512 |
|---|---|
| Product Name | XIAP Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | API3, BIR4, BIRC4, Baculoviral IAP repeat-containing protein 4, HILP, IAP-like protein, IAP3, Inhibitor of apoptosis protein 3 |
| Isotype | Rabbit IgG. |
| Reactivity | Human, Rat, Mouse. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminal of human XIAP, different from the related mouse sequence by two amino acids. |
| Purification | Immunogen affinity purified. |
| Form Of Antibody | Lyophilized. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal XIAP antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA003721-PA1512: XIAP Polyclonal Antibody
Introduction
BIRC4, baculoviral IAP repeat-containing protein 4 is also known as XIAP (X-linked inhibitor of apoptosis protein). The BIRC4 gene comprises 6 exons. This gene is mapped to chromosome Xq25. This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Other XIAP Antibody:
XIAP (Ab-87) Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug |
