WT1 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

WT1 Rabbit pAb

$108.00$488.00

In stock

$108.00$488.00

GUD; AWT1; WAGR; WT-1; WT33; NPHS4; WIT-2

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SKU: A1198
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Catalog No. A1198
Product NameWT1 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms GUD; AWT1; WAGR; WT-1; WT33; NPHS4; WIT-2
Gene Name WT1
Protein Name WT1
Uniprot/Swissprot ID P19544
Entrez GeneID 7490
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.

Additional information

Ship from Country

USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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