TP53BP1 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

TP53BP1 Rabbit pAb

$108.00$488.00

In stock

$108.00$488.00

p202; 53BP1; TDRD30; p53BP1

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SKU: A21632
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Catalog No. A21632
Product NameTP53BP1 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms p202; 53BP1; TDRD30; p53BP1
Gene Name TP53BP1
Protein Name TP53BP1
Uniprot/Swissprot ID Q12888
Entrez GeneID 7158
Clonality Polyclonal
Source/Host Rabbit
Applications IHC-P
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms.

Additional information

Ship from Country

USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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