TNFA Polyclonal Antibody

TNFA Polyclonal Antibody

$350.00

In stock

$350.00

Conditions of optimal TNFA polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA000215-PA1079
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Catalog No. PA000215-PA1079
Product NameTNFA Polyclonal Antibody
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms Tumor necrosis factor α Antibody
Isotype Rabbit IgG.
Specificity/Sensitivity Human, mouse, rat. No cross reactivity with other proteins.
Reactivity Human, Mouse, Rat.
Immunogen A peptide mapping at the C-terminal of TNFα of human origin, different from the mouse sequence by one amino acid, and rat sequence by three amino acids.
Purification Immunogen affinity purified.
Form Of Antibody Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Stability & Storage Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note Conditions of optimal TNF? antibody performance should be determined experimentally by the investigator.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA000215-PA1079: TNFA Polyclonal Antibody
Background

Tumor necrosis factor-alpha (TNFA) also kowns as TNFR1, It is a potent cytokine, elicits a broad spectrum of biologic responses which are mediated by binding to a cell surface receptor. There are 2 different proteins that serve as major receptors for TNF-alpha, one associated with myeloid cells and one associated with epithelial cells. TNFR1 maps to 12p13. TNFR1 signaling is also known to activate the transcription factor NF-kappa B and promote survival.Tumor necrosis factor, alpha-induced protein 1 (endothelial), also known as TNFAIP1, is a human gene.The gene, present in single copy, was located in the 17q22-q23 region. This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. The protein is involved in the primary response of the endothelium to TNF.
Other TNFα Antibody:
TNFα Monoclonal Antibody

TNF alpha Proteins:
Recombinant Rabbit TNFα Protein
Recombinant Mouse TNFα Protein
Recombinant Human TNFα Protein, His Tag
Recombinant Canine TNFα Protein
Recombinant Human TNFα Protein

TNFα ELISA Kits:
Rat TNFα ELISA Kit
Mouse TNFα ELISA Kit
Human TNFα ELISA Kit

Additional information

Ship from Country

USA

Size

100 ug

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