STIM1 Rabbit pAb
$108.00 – $488.00
GOK; TAM; TAM1; IMD10; STRMK; D11S4896E
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- Description
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| Catalog No. | A7411 |
|---|---|
| Product Name | STIM1 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | GOK; TAM; TAM1; IMD10; STRMK; D11S4896E |
| Gene Name | STIM1 |
| Protein Name | STIM1 |
| Uniprot/Swissprot ID | Q13586 |
| Entrez GeneID | 6786 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB, IHC-P, IF/ICC, IP |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3′ end of this gene situated 1.6 kb from the 5′ end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |