STAT5B Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

STAT5B Rabbit pAb

$108.00$488.00

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$108.00$488.00

STAT5; GHISID2

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SKU: A0275
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Catalog No. A0275
Product NameSTAT5B Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms STAT5; GHISID2
Gene Name STAT5B
Protein Name STAT5B
Uniprot/Swissprot ID P51692
Entrez GeneID 6777
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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