SOCS1 Polyclonal Antibody
$350.00
Conditions of optimal SOCS1 polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA000230-PA1074 |
|---|---|
| Product Name | SOCS1 Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | Suppressor of cytokine signaling 1 Antibody |
| Isotype | Rabbit IgG. |
| Specificity/Sensitivity | Human, mouse, rat. No cross reactivity with other proteins. |
| Reactivity | Human, Mouse, Rat. |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminal of human SOCS1, identical to the related mouse and rat sequence. |
| Purification | Immunogen affinity purified. |
| Form Of Antibody | Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal SOCS1 antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA000230-PA1074: SOCS1 Polyclonal Antibody
Background
Suppressor of cytokine signaling 1 (SOCS1), also known as Jak-binding protein (JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity.1 The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13.2 SOCS1 regulates the JAK/STAT signal-transduction pathway.3 Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.4.
Other SOCS1 Antibody:
SOCS1 Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug |
