SNAP23 Polyclonal Antibody
$350.00
Conditions of optimal SNAP23 polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA006658-PA1774 |
|---|---|
| Product Name | SNAP23 Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | Synaptosomal-Associated Protein, 23-KD, SNAP23A |
| Isotype | Rabbit IgG. |
| Reactivity | Human, Rat, Mouse. |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminal of human SNAP23, different from the related rat and mouse sequences by three amino acids . |
| Purification | Immunogen affinity purified. |
| Form Of Antibody | Lyophilized. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal SNAP23 Antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA006658-PA1774: SNAP23 Polyclonal Antibody
Introduction
SNAP23(Synaptosomal-Associated Protein, 23-KD), also called SNAP23A, is a protein that in humans is encoded by the SNAP23 gene. The SNAP23 gene has 8 exons, with the initiation codon located in exon 2. The SNAP23 gene is mapped on 15q15.1-q15.2. The SNAP23 cDNA encodes a 211-amino acid polypeptide with a predicted mass of 23 kD. Its amino acid sequence is 59% identical to that of SNAP25. Northern blot analysis revealed that SNAP23 is ubiquitously expressed. SNAP23 is able to bind to multiple syntaxins as well as to multiple vesicle-associated membrane proteins. After relocation, SNAP23 is required for exocytosis, implying a crucial role in promoting membrane fusion. TIVAMP-containing vesicles were concentrated in the apical domain of epithelial cells. STX3A and SNAP23 were codistributed at the apical plasma membrane, where they formed N-ethyl maleimide-dependent SNARE complexes with TIVAMP and cellubrevin. SNAP23 is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion.
Other SNAP23 Antibody:
Recombinant Human SNAP23 Protein
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug |
