Phospho-MLKL-S441 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Phospho-MLKL-S441 Rabbit pAb

$148.00$548.00

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$148.00$548.00

9130019I15Rik

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SKU: AP1174
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Catalog No. AP1174
Product NamePhospho-MLKL-S441 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms 9130019I15Rik
Gene Name Mlkl
Protein Name Mlkl
Uniprot/Swissprot ID Q9D2Y4
Entrez GeneID 74568
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Rat
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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