PCSK1 Rabbit pAb

Catalog No.	A12237
Product Name	PCSK1 Rabbit pAb
Supplier Name	ABclonal, Inc.
Brand Name	Abclonal
Synonyms	PC1; PC3; NEC1; SPC3; PC1/3; BMIQ12
Gene Name	PCSK1
Protein Name	PCSK1
Uniprot/Swissprot ID	P29120
Entrez GeneID	5122
Clonality	Polyclonal
Source/Host	Rabbit
Applications	WB, IF/ICC
Reactivity	Mouse, Rat
Conjugate	Unconjugated
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene

Additional information

Ship from Country	USA
Size	20 ul, 100 ul, 200 ul, 50 ul

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