NCAM1 / CD56 Rabbit pAb(A0393)

NCAM1 / CD56 Rabbit pAb(A0393)

$148.00$330.00

In stock

$148.00$330.00

CD56; NCAM; MSK39

SKU: A0393
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Catalog No. A0393
Product NameNCAM1 / CD56 Rabbit pAb(A0393)
Supplier Name Caprico Biotechnologies, Inc.
Brand Name Caprico
Synonyms CD56; NCAM; MSK39
Gene Name NCAM1
Protein Name NCAM1
Uniprot/Swissprot ID P13591
Entrez GeneID 4684
Clonality Polyclonal
Source/Host Rabbit
Applications FC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
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Description

A0393:NCAM1 / CD56 Rabbit pAb(A0393)

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. This protein is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. This protein plays a role in signal transduction by interacting with fibroblast growth factor receptors, N-cadherin and other components of the extracellular matrix and by triggering signalling cascades involving FYN-focal adhesion kinase (FAK), mitogen-activated protein kinase (MAPK), and phosphatidylinositol 3-kinase (PI3K). One prominent isoform of this gene, cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients whereas increased severity of COVID-19 is correlated with decreased abundance of CD56-expressing NK cells in peripheral blood. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.
Please remember our product information: NCAM1 / CD56 Rabbit pAb(A0393) catalog number: A0393 Caprico Biotechnologies

Additional information

Ship from Country

USA

Size

20 ul, 100 ul, 50 ul

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